Q:

"This file contained a virus and was deleted" on an executable I built (and code-signed)

I have built a Windows executable (with MSVC++) requiring administrator privilege to run (it indexes files) ; I even code-signed it with a code-signing certificate I bought.
It works well on Win7, Win8, but on Windows 10, if I download the file from the browser, then I get this message from IE/Edge: 

This file contained a virus and was deleted

and it's nearly impossible for a (non power-user) user to have access to the ZIP, extract it, and run the .exe. (It's very complicated to find the right quarantine place, and remove it from quarantine, etc.; and also it's non-ok for a commercial product)
It's clearly a false positive (I have no virus, and I checked it with many antivirus, and https://www.virustotal.com).
What solution is there? (I thought I had tried all I can do by even code-signing it with a certificate from a well-known CA)

A:

The file was detected by Windows Defender as a file system indexer. All these files could be considered as a threat. You should report your file as safe to Microsoft.

